Pathogens and Immunity Interdisciplinary Group
University of Georgia
Characterizing the assembly of bacterial surface structures, Development of vaccines for viral
and bacterial pathogens, Systems approaches to understanding microbial diseases
Mechanisms of immune activation by carbohydrate antigens; design and development
of knowledge-based vaccines and therapeutics against pathogens and cancers.
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Antibiotic & antiviral drug discovery, assay development, enzymology,
and structural biology, regulation of innate immune responses.
Molecular helminthology: in particular the interactions of
anthelmintic drugs with ion channels in the nervous systems
of parasitic helminths, and the molecular basis of drug resistance.
Transmission and pathogenicity of zoonotic influenza virus infection and development
of vaccination and the prevention and treatment of viral infections.
Metabolism and drug development against protozoan parasites.
Calcium signaling and storage in Toxoplasma gondii.
X-ray crystallography of macromolecules, prokaryotic transcriptional regulators.
Cell Signaling, Organelle Biogenesis, and Drug Discovery in Trypanosomes.
Mechanistic analysis of parasite induced immune suppression. Translational research
on immuno-modulation pertaining to inflammation based diseases.
Vaccine development and trials.
Cellular and molecular biology of acidocalcisomes; the role of polyphosphate in trypanosomatids.
