Pathogens and Immunity Interdisciplinary Group
University of Georgia
Antibiotic & antiviral drug discovery, assay development, enzymology,
and structural biology, regulation of innate immune responses.
Veterinary diagnostics; emerging clinical problems; antibiotic resistance;
epidemiology of diseases with special emphasis in zoonoses.
Mechanisms of bacterial virulence and survival in the host; host-pathogen interactions;
vaccine development.
Molecular and cellular biology of the human malaria parasite, Plasmodium falciparum.
Characterization of adhesion proteins which mediate host-parasite interactions in Plasmodium falciparum.
Molecular helminthology: in particular the interactions of
anthelmintic drugs with ion channels in the nervous systems
of parasitic helminths, and the molecular basis of drug resistance.
Regulation of host defense and tolerance by Stat transcription factors.
Transmission and pathogenicity of zoonotic influenza virus infection and development
of vaccination and the prevention and treatment of viral infections.
We study CRISPR-Cas immune systems that protect prokaryotes from viruses and provide
powerful research tools for important biotechnology and biomedical applications.
Mechanisms of immunity and disease in Trypanosoma cruzi infection (Chagas Disease); Basic and applied biology of T. cruzi.
